Listar por autor "JANICE L. ALLEN"
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Mitochondrial genetic diversity, selection and recombination in a canine transmissible cancer
Canine transmissible venereal tumour (CTVT) is a clonally transmissible cancer that originated approximately 11,000 years ago and affects dogs worldwide. Despite the clonal origin of the CTVT nuclear genome, CTVT mitochondrial ... -
Recurrent horizontal transfer identifies mitochondrial positive selection in a transmissible cancer
Autonomous replication and segregation of mitochondrial DNA (mtDNA) creates the potential for evolutionary conflict driven by emergence of haplotypes under positive selection for ‘selfish’ traits, such as replicative ...